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What is the most important information I should know about Plendil?
• Do not stop taking Plendil without first talking to your doctor, evenif you begin to feel better plendil er10mg. If you stop taking the medication, your conditioncould become worse plendil er10mg.
• Brush and floss your teeth regularly as directed by your dentist plendil er10mg. Rarely,swelling of the gums may be a side effect from treatment with Plendil plendil er10mg. Properoral hygiene may alleviate these symptoms plendil er10mg.
• Do not crush, chew, or break the tablets plendil er10mg. Swallow them whole plendil er10mg.
• Grapefruit and grapefruit juice may interact with Plendil plendil er10mg. The interactioncould lead to potentially dangerous effects plendil er10mg. Discuss the use of grapefruit andgrapefruit juice with your doctor plendil er10mg. Do not increase or decrease the amount ofgrapefruit products in your diet without first talking to your doctor plendil er10mg.


What is Plendil?
• Plendil is in a class of drugs called calcium channel blockers plendil er10mg. Plendilrelaxes (widens) your blood vessels (veins and arteries), which makes it easierfor the heart to pump and reduces its workload plendil er10mg.
• Plendil is used to treat hypertension (high blood pressure) plendil er10mg.
• Plendil may also be used for purposes other than those listed in thismedication guide plendil er10mg.


What should I discuss with my healthcare provider before taking Plendil?
• Before taking Plendil, tell your doctor if you have
· liver disease; or
· another disease of the heart or blood vessels such as sick sinus syndrome,aortic stenosis, heart failure, low blood pressure, or coronary artery disease plendil er10mg.
• You may not be able to take Plendil, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove plendil er10mg.
• Plendil is in the FDA pregnancy category C plendil er10mg. This means that it is notknown whether Plendil will be harmful to an unborn baby plendil er10mg. Do not take this medicationwithout first talking to your doctor if you are pregnant or could become pregnantduring treatment plendil er10mg.
• It is not known whether Plendil passes into breast milk plendil er10mg. Do not takePlendil without first talking to your doctor if you are breast-feeding a baby plendil er10mg.
• If you are over 65 years of age, you may be more likely to experienceside effects from Plendil plendil er10mg. Your doctor may prescribe a lower dose of this medication plendil er10mg.


How should I take Plendil?
• Take Plendil exactly as directed by your doctor plendil er10mg. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you plendil er10mg.
• Take each dose with a full glass of water plendil er10mg.
• Take each dose consistently either without food or with a light meal plendil er10mg.
• Do not crush, chew, or break the tablets plendil er10mg. Swallow them whole plendil er10mg.
• Do not stop taking Plendil without first talking to your doctor, evenif you begin to feel better plendil er10mg. If you stop taking the medication, your conditioncould become worse plendil er10mg.
• Grapefruit and grapefruit juice may interact with Plendil plendil er10mg. The interactioncould lead to potentially dangerous effects plendil er10mg. Discuss the use of grapefruit andgrapefruit juice with your doctor plendil er10mg. Do not increase or decrease the amount ofgrapefruit products in your diet without first talking to your doctor plendil er10mg.
• Brush and floss your teeth regularly as directed by your dentist plendil er10mg. Rarely,swelling of the gums may be a side effect from treatment with Plendil plendil er10mg. Properoral hygiene may alleviate these symptoms plendil er10mg.
• Store Plendil at room temperature away from moisture and heat plendil er10mg.


What happens if I miss a dose?
• Take the missed dose as soon as you remember plendil er10mg. However, if it is almosttime for the next dose, skip the missed dose and take only the next regularlyscheduled dose plendil er10mg. Do not take a double dose of this medication plendil er10mg.


What happens if I overdose?
• Seek emergency medical attention plendil er10mg.
• Symptoms of a Plendil overdose include dizziness, weakness, chest pain,shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurredspeech, and confusion plendil er10mg.


What should I avoid while taking Plendil?
• Grapefruit and grapefruit juice may interact with Plendil plendil er10mg. The interactioncould lead to potentially dangerous effects plendil er10mg. Discuss the use of grapefruit andgrapefruit juice with your doctor plendil er10mg. Do not increase or decrease the amount ofgrapefruit products in your diet without first talking to your doctor plendil er10mg.
• Follow any recommendations your doctor makes about diet or exercise plendil er10mg.
• Use caution when you stand or sit up from a lying position, especiallyif you wake up during the night plendil er10mg. You may become dizzy when changing positions plendil er10mg.
• Use alcohol cautiously plendil er10mg. Alcohol may further lower blood pressure andincrease drowsiness or dizziness while taking Plendil plendil er10mg.


What are the possible side effects of Plendil?
• If you experience any of the following serious side effects, stop takingPlendil and contact your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of the throat;swelling of the lips, tongue, or face; or hives);
· unusually fast or slow heartbeat;
· chest pain;
· severe dizziness or fainting;
· abnormal behavior or psychosis;
· jaundice (yellowing of the skin or eyes), or
· swelling of the legs, ankles, or face plendil er10mg.
• Other, less serious side effects may be more likely to occur plendil er10mg. Continueto take Plendil and talk to your doctor if you experience
· fatigue or tiredness;
· headache;
· insomnia or difficulty sleeping;
· swelling of your gums;
· nausea or diarrhea;
· increased or difficult urination;
· muscle or joint discomfort; or
· flushing (redness) plendil er10mg.
• Side effects other than those listed here may also occur plendil er10mg. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome plendil er10mg.


What other drugs will affect Plendil?
• Before taking Plendil, tell your doctor if you are taking any of thefollowing drugs:
· another heart medication to treat the same or another condition;
· erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, others);
· itraconazole (Sporanox) or ketoconazole (Nizoral);
· cimetidine (Tagamet, Tagamet HB);
· carbamazepine (Tegretol);
· phenytoin (Dilantin); or
· rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin) plendil er10mg.
• You may not be able to take Plendil, or you may require a dosage adjustmentor special monitoring if you are taking any of the medicines listed above plendil er10mg.
• Drugs other than those listed here may also interact with Plendil oraffect your condition plendil er10mg. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines, including herbal products plendil er10mg.


Where can I get more information?
• Your pharmacist has additional information about Plendil written forhealth professionals that you may read plendil er10mg.


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